Table 2 Migraine Interictal Burden Scale (MIBS-4) and Headache Impact Test (HIT-6) overall and stratified by CGRP mAb treatment experience (3+ months) and chronic migraine (CM) diagnosis
From: Measuring interictal burden among people affected by migraine: a descriptive survey study
Characteristic | Overall, N = 506 | No CGRP mAb, n = 311 | CGRP mAb, n = 195 | No CM, n = 267 | CM, n = 239 |
|---|---|---|---|---|---|
Interictal burden | |||||
 MIBS-4 Score (0–12) | |||||
  Mean (SD) | 6.3 (3.4) | 5.3 (3.3) | 7.9 (3.1) | 5.5 (3.4) | 7.2 (3.3) |
 Level of interictal burden | |||||
  None (0) | 22 (4%) | 20 (6%) | 2 (1%) | 15 (6%) | 7 (3%) |
  Mild (1, 2) | 72 (14%) | 60 (19%) | 12 (6%) | 51 (19%) | 21 (9%) |
  Moderate (3, 4) | 72 (14%) | 54 (17%) | 18 (9%) | 47 (18%) | 25 (10%) |
  Severe (≥5) | 340 (67%) | 177 (57%) | 163 (84%) | 154 (58%) | 186 (78%) |
Headache/ migraine impact | |||||
 HIT-6 Scale (36–78) | |||||
  Mean (SD) | 65.3 (6.0) | 65.1 (6.2) | 65.7 (5.5) | 64.3 (6.3) | 66.5 (5.4) |
 Level of impact | |||||
  Little or no (≤49) | 5 (1%) | 4 (1%) | 1 (1%) | 4 (2%) | 1 (0%) |
  Some (50–55) | 28 (6%) | 20 (6%) | 8 (4%) | 19 (7%) | 9 (4%) |
  Substantial (56–59) | 39 (8%) | 26 (8%) | 13 (7%) | 29 (11%) | 10 (4%) |
  Severe (≥60) | 434 (86%) | 261 (84%) | 173 (89%) | 215 (81%) | 219 (92%) |