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Table 1 Demographic and clinical characteristics of migraine patients at baseline and in non-persistent and persistent study groups

From: Persistence, use of resources and costs in patients under migraine preventive treatment: the PERSEC study

 

Entire study population

N = 7,866 (100%)

Non-persistent patients

N = 5,414 (69.4%)

Persistent patients

N = 2,390 (30.6%)

Age, years

 Mean (SD)

48.2 (14.8)

47.6 (14.7)

48.8 (14.3)

Age range, n (%)

 18—44 years

3,296 (41.9%)

2,343 (43.3%)

949 (39.6%)

 45—64 years

3,527 (44.8%)

2,384 (44.1%)

1,127 (47.1%)

 65—74 years

713 (9.1%)

479 (8.9%)

223 (9.3%)

  ≥ 75 years

330 (4.2%)

204 (3.8%)

95 (4.0%)

Gender (women), n (%)

6,324 (80.4%)

4,361 (80.6%)

1,918 (80.3%)

BMI, kg/m2

 Mean (SD)

27.8 (4.5)

27.7 (4.5)

27.9 (4.3)

Time since diagnosis, yearsa

 Mean (SD)

3.6 (1.9)

3.6 (1.9)

3.7 (1.9)

Comorbidities per patient

 Mean (SD)

1.6 (1.4)

1.6 (1.4)

1.6 (1.4)

CCI

 Mean (SD)

0.4 (0.9)

0.4 (0.9)

0.4 (0.9)

Comorbidities, n (%)

 Generalized anxiety disorder

2,827 (35.9%)

1,968 (36.4%)

813 (34.0%)

 Dyslipidaemia

2,124 (27.0%)

1,445 (26.7%)

648 (27.1%)

 Arterial hypertension

1,724 (21.9%)

1,170 (21.6%)

524 (21.9%)

 Obesity

1,161 (14.8%)

794 (14.7%)

353 (14.8%)

 Depressive syndrome

890 (11.3%)

607 (11.2%)

272 (11.4%)

 Asthma

622 (7.9%)

450 (8.3%)

166 (6.9%)

 Malignant neoplasms

620 (7.9%)

439 (8.1%)

168 (7.0%)

 Diabetes

529 (6.7%)

397 (7.3%)

118 (4.9%)

 COPD

220 (2.8%)

154 (2.8%)

63 (2.6%)

 Stroke

170 (2.2%)

112 (2.1%)

55 (2.3%)

 Ischaemic heart disease

115 (1.5%)

69 (1.3%)

41 (1.7%)

 Kidney failure

121 (1.5%)

85 (1.6%)

30 (1.3%)

 Heart failure

99 (1.3%)

62 (1.1%)

31 (1.3%)

Other risk factors, n (%)

 Active smoking

1,426 (18.1%)

922 (17.0%)

478 (20.0%)

  1. BMI body mass index, CCI Charlson Comorbidity Index, COPD chronic obstructive pulmonary disease, SD standard deviation
  2. aThe Big-Pac™ database contains data from 2012 onwards. For patients diagnosed before 2012, we assumed the first entry in the database as the date of diagnosis