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Table 1 Demographic and clinical characteristics of migraine patients at baseline and in non-persistent and persistent study groups

From: Persistence, use of resources and costs in patients under migraine preventive treatment: the PERSEC study

  Entire study population
N = 7,866 (100%)
Non-persistent patients
N = 5,414 (69.4%)
Persistent patients
N = 2,390 (30.6%)
Age, years
 Mean (SD) 48.2 (14.8) 47.6 (14.7) 48.8 (14.3)
Age range, n (%)
 18—44 years 3,296 (41.9%) 2,343 (43.3%) 949 (39.6%)
 45—64 years 3,527 (44.8%) 2,384 (44.1%) 1,127 (47.1%)
 65—74 years 713 (9.1%) 479 (8.9%) 223 (9.3%)
  ≥ 75 years 330 (4.2%) 204 (3.8%) 95 (4.0%)
Gender (women), n (%) 6,324 (80.4%) 4,361 (80.6%) 1,918 (80.3%)
BMI, kg/m2
 Mean (SD) 27.8 (4.5) 27.7 (4.5) 27.9 (4.3)
Time since diagnosis, yearsa
 Mean (SD) 3.6 (1.9) 3.6 (1.9) 3.7 (1.9)
Comorbidities per patient
 Mean (SD) 1.6 (1.4) 1.6 (1.4) 1.6 (1.4)
CCI
 Mean (SD) 0.4 (0.9) 0.4 (0.9) 0.4 (0.9)
Comorbidities, n (%)
 Generalized anxiety disorder 2,827 (35.9%) 1,968 (36.4%) 813 (34.0%)
 Dyslipidaemia 2,124 (27.0%) 1,445 (26.7%) 648 (27.1%)
 Arterial hypertension 1,724 (21.9%) 1,170 (21.6%) 524 (21.9%)
 Obesity 1,161 (14.8%) 794 (14.7%) 353 (14.8%)
 Depressive syndrome 890 (11.3%) 607 (11.2%) 272 (11.4%)
 Asthma 622 (7.9%) 450 (8.3%) 166 (6.9%)
 Malignant neoplasms 620 (7.9%) 439 (8.1%) 168 (7.0%)
 Diabetes 529 (6.7%) 397 (7.3%) 118 (4.9%)
 COPD 220 (2.8%) 154 (2.8%) 63 (2.6%)
 Stroke 170 (2.2%) 112 (2.1%) 55 (2.3%)
 Ischaemic heart disease 115 (1.5%) 69 (1.3%) 41 (1.7%)
 Kidney failure 121 (1.5%) 85 (1.6%) 30 (1.3%)
 Heart failure 99 (1.3%) 62 (1.1%) 31 (1.3%)
Other risk factors, n (%)
 Active smoking 1,426 (18.1%) 922 (17.0%) 478 (20.0%)
  1. BMI body mass index, CCI Charlson Comorbidity Index, COPD chronic obstructive pulmonary disease, SD standard deviation
  2. aThe Big-Pac™ database contains data from 2012 onwards. For patients diagnosed before 2012, we assumed the first entry in the database as the date of diagnosis