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Table 2 Serum levels of NGF, BDNF, VEGF and PGE2 biomarkers in study groups

From: Assessment of peripheral biomarkers potentially involved in episodic and chronic migraine: a case-control study with a focus on NGF, BDNF, VEGF, and PGE2

Biomarker

Episodic migraine (n=23)

Chronic migraine (n=36)

Controls (n=30)

P-value

 

Median (IQR)

Median (IQR)

Median (IQR)

 

NGF

63.11 (24.56) *, #

75.88 (31.89) *

90.58 (70.25) #

0.009

BDNF

0.49 (0.13) *

0.49 (0.14) #

1.05 (0.96) *, #

<0.001

VEGF

937.41 (230.23)

932.56 (301.35)

646.50 (292.50)

0.046

PGE2

120.71 (19.47)*

134.16 (38.57)

153.50 (55.69)*

0.001

  1. ¶: Across group comparison (Kruskal-Wallis); *, #: significant adjusted P-value for pairwise-comparison (Dunn-Bonferroni); NGF: nerve growth factor; BDNF: brain-derived neurotrophic factor; VEGF: vascular endothelial growth factor; PGE2: prostaglandin E2
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The Journal of Headache and Pain

ISSN: 1129-2377

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