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Fig. 4 | The Journal of Headache and Pain

Fig. 4

From: IL-17 crosses the blood–brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine

Fig. 4

Migrainous mediators of the TNC and TG in rats with NTG-induced migraine. (A) The expression of the CGRP mRNA in the TNC of rats with NTG-induced migraine. (B) The expression of the CGRP mRNA in the TG of rats with NTG-induced migraine. (C) CGRP contents in the TNC of rats with NTG-induced migraine. *p < 0.05 compared to control group. (D) The variation in NOS levels in the TNC of rats with NTG-induced migraine. *p < 0.05 compared to the 2.5 mg/kg daily group; #p < 0.05 compared to the 5 mg/kg every 2 d group. (E) The protein expression of the c-Fos in the TNC of rats with NTG-induced migraine. Statistical analysis was performed using one–way ANOVA, n = 3

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The Journal of Headache and Pain

ISSN: 1129-2377

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