Table 2 Correlation (Pearson’s r) between change in GABA+ levels and change in measures of headache frequency, pain intensity and disability in people with migraine (n = 18)
Neurometabolite Levels | Change in frequency (days/month) r (p-value) | Change in intensity (HIT-6) r (p-value) | Change in disability (WHODAS) r (p-value) | |
|---|---|---|---|---|
Change in GABA+ | PCG | −0.10 (0.69) | 0.01 (0.96) | −0.23 (0.38) |
ACC | −0.51 (0.03)* | − 0.51 (0.03)* | − 0.53 (0.02)* | |
Change in Glx | PCG | 0.08 (0.74) | −0.07 (0.8) | 0.09 (0.74) |
ACC | −0.30 (0.23) | −0.32 (0.2) | −0.40 (0.10) | |