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Table 4 Incidence of common TEAEs with lasmiditan (100 mg and 200 mg dose groups pooled) across attacks in patients who treated 4 attacks

From: Safety findings from CENTURION, a phase 3 consistency study of lasmiditan for the acute treatment of migraine

 

Reported an event, n (%)

Fatigue

Nausea

Paresthesia

Somnolence

Vertigo

Reported TEAE in Attack 1

 N=494a

 Attack 1

37

27

44

29

26

 Attack 2

6 (16.2)b

12 (44.4)

19 (43.2)

10 (34.5)

9 (34.6)

 Attack 3

5 (13.5)

5 (18.5)

19 (43.2)

10 (34.5)

8 (30.8)

 Attack 4

7 (18.9)

11 (40.7)

14 (31.8)

5 (17.2)

10 (38.5)

Did NOT report TEAE in Attack 1

 N=457

 N=467

 N=450

 N=465

 N=468

 Attack 1

0

0

0

0

0

 Attack 2

12 (2.6)c

14 (3.0)

24 (5.3)

8 (1.7)

9 (1.9)

 Attack 3

17 (3.7)

11 (2.4)

17 (3.8)

6 (1.3)

8 (1.7)

 Attack 4

13 (2.8)

13 (2.8)

18 (4.0)

5 (1.1)

11 (2.4)

  1. aPatients in safety population treating all 4 attacks
  2. bDenominator is number who reported an event in Attack 1
  3. cDenominator is number who did not report an event in Attack 1