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Table 3 Psychological characteristics of the two groups as result from self-reported questionnaires at the baseline evaluation. Data are presented as “mean ± standard deviation”

From: Psychological predictors of negative treatment outcome with Erenumab in chronic migraine: data from an open label long-term prospective study

 

Responders

N = 53

Non Responders

N = 22

p

HADS Depression

6.1 ± 4.6

7.5 ± 5.3

0.28

HADS Anxiety

6.1 ± 4.1

7.1 ± 4.1

0.35

Childhood Trauma Questionnaire

 Important traumas

0.4 ± 0.8

0.5 ± 1.3

0.65

 Serious traumas

0.1 ± 0.4

0.3 ± 0.6

0.21

 Very serious traumas

0.3 ± 0.7

0.4 ± 1.0

0.62

 At least serious traumas

0.4 ± 0.9

0.6 ± 1.6

0.38

 Total traumas

1.3 ± 1.5

1.4 ± 2.4

0.83

Stressful life-events Questionnaire

 Important events

2.5 ± 2.7

3.2 ± 4.7

0.41

Serious events

0.5 ± 1.1

1.4 ± 1.8

0.012

Very serious events

0.3 ± 0.7

1.9 ± 2.9

< 0.001

‘At least serious’ events

0.8 ± 1.4

3.2 ± 4.0

< 0.001

Total stressful events

7.1 ± 5.2

10.7 ± 9.8

0.044

TAS-20

Total score

42.9 ± 14.3

51.7 ± 13.7

0.017

Factor 1

14.2 ± 7.6

19.1 ± 7.0

0.011

 Factor 2

11.3 ± 5.0

13.1 ± 4.9

0.17

 Factor 3

17.4 ± 5.4

19.6 ± 6.8

0.15

  1. HADS Hospital Anxiety and Depression Scale, TAS-20 Toronto Alexithymia Scale. Significant differences are bolded