Table 2 Change from baseline in quality of life measures and number of monthly migraine headache days with acute medication use at Month 3^a

MSQ total score

n = 84

n = 94

n = 41

n = 40

n = 43

n = 54

Change from baseline, mean (SE)

11.6 (2.6)

26.0 (2.5)

5.7 (3.1)

24.4 (3.4)

13.6 (3.4)

22.1 (3.2)

Difference, mean (SE)

P

MSQ role function restrictive

n = 84

n = 94

n = 41

n = 40

n = 43

n = 54

Change from baseline, mean (SE)

12.0 (2.8)

27.3 (2.7)

4.7 (3.4)

25.2 (3.6)

14.5 (3.6)

22.7 (3.4)

Difference, mean (SE)

P

MSQ role function emotional

n = 84

n = 94

n = 41

n = 40

n = 43

n = 54

Change from baseline, mean (SE)

14.5 (3.2)

28.9 (3.1)

9.2 (4.0)

28.3 (4.4)

14.7 (4.1)

24.2 (4.0)

Difference, mean (SE)

P

0.0003

0.0479

MSQ role function preventive

n = 84

n = 94

n = 41

n = 40

n = 43

n = 54

Change from baseline, mean (SE)

8.8 (2.5)

21.4 (2.4)

3.5 (3.1)

18.7 (3.3)

10.9 (3.2)

19.2 (3.0)

Difference, mean (SE)

P

Migraine Disability Assessment total score

n = 85

n = 95

n = 42

n = 40

n = 43

n = 55

Change from baseline, mean (SE)

−2.5 (6.6)

−28.2 (6.5)

8.9 (10.5)

−31.0 (11.8)

−8.0 (5.4)

−18.2 (5.2)

Difference

P

Number of monthly migraine headache days with acute medication use

n = 86

n = 98

n = 42

n = 42

n = 44

n = 56

Change from baseline, mean (SE)

−0.7 (0.7)

−5.3 (0.7)

−0.8 (1.0)

−7.0 (1.1)

−0.7 (0.8)

−3.5 (0.7)

Difference, mean (SE)

P