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Fig. 2 | The Journal of Headache and Pain

Fig. 2

From: Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms

Fig. 2

Expression and cell viability of mutant Na+/K+-ATPase. a Western blot of total membrane and plasma membrane proteins expressed in transfected HeLa cells (ATP1A2: 102 kDa; Tubulin: 50 kDa). The colored labels represented different groups: blue, WT; yellow, FHM; green, FHME; red, FHMEI. b The ATP1A2 expression of mutants was equal to that of the WT (compared with WT, TM: P = 0.3822, PM: P = 0.5507, Kruskal-Wallis test). c and d Cell survival assays. All mutants showed a significantly reduced survival rate under 1 µM ouabain in both HEK293T (c) and HeLa (d) cells (P < 0.0001, two-way ANOVA)

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The Journal of Headache and Pain

ISSN: 1129-2377

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