Whole-brain morphological alterations associated with trigeminal neuralgia

Table 1 Patient demographic information

	TN	HFS	CON	Statistic
Numbers	43	40	43	/
Age, y	59.05 ± 9.95	51.50 ± 9.04	58.95 ± 9.40	TN vs. HFS: t = 3.61, P < 0.05*, MD = 2.09, 95 % CI = 3.38–11.71 TN vs. CON: t = 0.05, P = 0.97, MD = 0.09, 95 % CI = -4.06-4.24
Sex, female (%)	23 (53.49 %)	24 (60.00 %)	24 (55.81 %)	TN vs. HFS: Chi = 0.36, P = 0.55, OR = 0.77, 95 % CI = 0.32–1.83 TN vs. CON: Chi = 0.05, P = 0.83, OR = 0.91, 95 % CI = 0.39–2.13
Side, left (%)	21 (48.84 %)	24 (60.00 %)	/	TN vs. HFS: Chi = 1.04, P = 0.31, OR = 0.64, 95 % CI = 0.27–1.52
Duration, y	5.41 ± 4.71	/	/	/
Distribution of the pain (n, %)	V1 = 1 (2.32 %) V12 = 1 (2.32 %) V123 = 3 (6.98 %) V2 = 12 (27.91 %) V23 = 10 (23.26 %) V3 = 16 (37.21 %)	/	/	/

Continuous and categorical data were respectively analyzed via independent-samples t-test and Chi-squared variance test
Abbreviations: TN patients with trigeminal neuralgia, HFS disease controls with hemifacial spasm, CON healthy controls, MD mean difference, 95 % CI 95 % confidence interval of the difference, OR odds ratio

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