Fig. 4
From: Whole-brain morphological alterations associated with trigeminal neuralgia
Systematic review of whole-brain studies assessing TN-related neuroimaging patterns. Sample size and quantitative MRI approaches are indicated along with reported findings (Red: increased cortical thickness or volume; Blue: decreased cortical thickness or volume, light blue: significant outcomes without correction; white: no assessment) across 3 brain subsystems (neocortical, subcortical structures and brainstem). VBM: voxel-based morphometry; CTA: cortical thickness analysis; SSA: surface-based shape analysis; FDR: false discovery rate; FWE: family-wise error; M1: primary somatosensory cortex; Fron. pole: frontal pole; OFC: orbitofrontal cortex; dPFC: dorsolateral prefrontal cortex; MFG: middle frontal gyrus; IFG: inferior frontal gyrus; ACC: anterior cingulate cortex; MCC: midcingulate cortex; PCC: posterior cingulate cortex; AG: angular gyrus; Ant.Ins: anterior insula; Post.Ins: posterior insula; Fusi: fusiform gyrus; Nac: nucleus accumbens; Amyg: amygdala; Cd: caudate nucleus; Thal: thalamus; PAG: periaqueductal gray