Mild traumatic brain injury affects the features of migraine

Table 6 Past history of abuse and psychiatric disorders

	Total	mTBI group	non-TBI group	P-value^a	Gender, age, CM controlled P-value^c
Number	1054	413	641
Any history of abuse
Yes	308 (36.8%)	162 (47.0%)	146 (29.7%)	< 0.001^b	< 0.001
No	528 (63.2%)	183 (53.0%)	345 (70.3%)
Missing	218	68	150
History of physical abuse
Yes	154 (18.4%)	84 (24.3%)	70 (14.3%)	< 0.001^b	< 0.001
No	682 (81.6%)	261 (75.7%)	421 (85.7%)
Missing	218	68	150
Depression (PHQ-2 Score)
Mean (SD)	1.4 ± 1.7	1.6 ± 1.8	1.3 ± 1.6	0.034^d	0.012
Median (IQR)	1 (0–2)	1 (0–2)	1 (0–2)
Missing	115	43	72
Anxiety (GAD-7 grade)
Minimal	573 (55.3%)	201 (49.5%)	372 (59.0%)	0.003^b	0.003
Mild-Severe	463 (44.7%)	205 (50.5%)	258 (41.0%)
Missing	18	7	11
PTSD
Yes	122 (26.2%)	68 (33.3%)	54 (20.7%)	0.002^b	0.002
No	343 (73.8%)	136 (66.7%)	207 (79.3%)
Missing	589	209	380

^aBolded text indicates significant difference. ^bChi-square test. ^cLogistic regression model was performed, controlling for age, gender, and chronic migraine. ^dMann-Whitney test. CM Chronic Migraine, GAD-7 General Anxiety Disorder-7, IQR interquartile range, mTBI mild traumatic brain injury, PHQ-2 Patient Health Questionnaire-2, PTSD Post-traumatic stress disorder, SD significant difference

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