Table 3 Results obtained from the statistical analysis performed on Cortical Thickness and Local Gyrification Index

Patients vs. Controls

Patients < Controls

n° Vertices

Mean p value

Controls Mean LGI (STD)

Patients Mean LGI (STD)

Left supramarginal gyrus

1262

0.01

3.53 (2.40)

3.51 (2.33)

Left superior parietal gyrus

1014

0.01

3.68 (2.57)

3.65 (2.52)

Left inferior parietal gyrus

256

0.02

4.03 (2.74)

4.00 (2.66)

Subgroups of Patients

Females < Males

n° Vertices

Mean p value

F Mean LGI (STD)

M Mean LGI (STD)

Right postcentral gyrus

187

0.05

3.40 (1.81)

3.49 (1.88)

Right supramarginal gyrus

888

0.05

3.25 (1.79)

3.30 (1.87)

Right superior temporal gyrus

724

0.04

3.41 (2.09)

3.47 (2.17)

Right middle temporal gyrus

111

0.05

3.95 (2.67)

4.04 (2.75)

Right transverse temporal gyrus

405

0.04

3.30 (2.01)

3.37 (2.09)

CORTICAL THICKNESS

Subgroups of Patients

Patients < 12y > Patients ≥ 12y

n° Vertices

Mean p value

Patients < 12y Mean CT (STD) in mm

Patients ≥ 12y Mean CT (STD)

Left superior frontal gyrus

356

0.02

2.43 (0.98)

2.36 (0.96)

Left middle frontal gyrus

434

0.02

2.78 (0.67)

2.71 (0.65)

Left precentral gyrus

3914

0.02

2.74 (0.73)

2.67 (0.71)

Left postcentral gyrus

705

0.02

2.67 (0.74)

2.61 (0.72)

Left paracentral lobule

1186

0.02

2.61 (0.85)

2.54 (0.83)

Left superior temporal gyrus

739

0.03

2.73 (0.74)

2.65 (0.72)

Left transverse temporal gyrus

427

0.03

2.66 (0.78)

2.58 (0.76)

Left supramarginal gyrus

523

0.03

2.71 (0.80)

2.64 (0.79)

Left posterior insula

361

0.03

2.64 (0.74)

2.56 (0.72)

Patients with nausea and/or vomiting > Patients without nausea and/or vomiting

n° Vertices

Mean p value

Patients without nausea and/or vomiting Mean CT (STD) in mm

Patients with nausea and/or vomiting Mean CT (STD)

Left pars opercularis

113

0.04

2.52 (0.94)

2.48 (0.92)