Table 1 Mechanical and thermal orofacial pain sensitivity tested by air puff test and acetone drop on trigeminal neuralgia and sham rat models
Air puff Threshold (psi) | |||||
Animal groups | Baseline | Day 3 | Day 7 | Day 15 | Day 21 |
TN ipsilateral | 18.50 ± 2.23 | 10.21 ± 1.50**** | 9.20 ± 1.43**** | 8.50 ± 1.34**** | 7.20 ± 1.26**** |
TN contralateral | 18.35 ± 2.89 | 19 ± 0.25 | 18.45 ± 2.10 | 19.01 ± 1.88 | 18.23 ± 1.67 |
Sham ipsilateral | 19.36 ± 2.35 | 18.57 ± 3.19 | 17.81 ± 1.75 | 20.12 ± 1.74 | 19.42 ± 2.90 |
Sham contralateral | 19.12 ± 0.35 | 17.29 ± 2.25 | 19.29 ± 1.75 | 19.59 ± 1.77 | 17.25 ± 3.72 |
Cold hyperalgesia (No. of responses) | |||||
Baseline | Day 3 | Day 7 | Day 15 | Day 21 | |
TN | 7.76 ± 4.38 | 15.98 ± 3.28**** | 18 ± 4.45**** | 25.98 ± 3.17**** | 24.68 ± 2.80**** |
sham | 9 ± 2.34 | 10.12 ± 1.75 | 10.31 ± 1.93 | 9.14 ± 1.25 | 9.33 ± 1.01 |