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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Differential alteration of fMRI signal variability in the ascending trigeminal somatosensory and pain modulatory pathways in migraine

Fig. 3

Cross-correlation of the resting-state BOLD signal time course. Cross-correlation of the BOLD signal within the trigeminal spinal-thalamo-cortical pathway (a), which was increased BOLDSV and right frontoparietal region (b), which was decreased BOLDSV. Blue and red masks in the brain image indicate the locations of the maximum difference of BOLDSV within the frequency of 0.01–0.198 Hz except for S1, which was significant in the slow-4 (0.027–0.073 Hz) band. All time courses (0.01–0.198 Hz) were extracted from masks (5-mm sphere) to calculate cross-correlation between the regions. The blue and red lines indicate grand averaged cross-correlation across all 46 subjects. The upper and lower horizontal dotted lines indicate the approximate 95% confidence bounds

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