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Table 2 GBD2019: Top level-4 causes of global disability (expressed as years lived with disability [YLDs]) by gender and age (data from [3, 4])

From: Migraine remains second among the world’s causes of disability, and first among young women: findings from GBD2019

Gender Age range (years) Rank Cause % of total YLDs [uncertainty interval]
Both All 1 Low back pain 7.4 [6.2–8.7]
2 Migraine 4.9 [0.8–10.1]
3 Age-related hearing loss 4.7 [3.8–5.7]
15–49 1 Low back pain 7.6 [6.1–9.3]
2 Migraine 7.3 [1.1–15.1
3 Major depression 5.8 [4.3–7.5]
Male All 1 Low back pain 7.0 [5.8–8.2
2 Age-related hearing loss 5.2 [4.3–6.4]
3 Diabetes type 2 4.7 [4.0–5.4]
4 Migraine 4.1 [0.7–8.3]
15–49 1 Low back pain 7.8 [6.3–9.6]
2 Migraine 6.3 [1.1–12.8]
3 Major depression 5.2 [3.8–6.7]
Female All 1 Low back pain 7.7 [6.5–9.2]
2 Migraine 5.5 [0.9–11.6]
3 Other musculoskeletal 5.0 [3.8–6.4]
15–49 1 Migraine 8.0 [1.2–16.7]
2 Low back pain 7.4 [5.9–9.1]
3 Major depression 6.2 [4.6–8.2]