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Table 3 Synaptic ultrastructure parameters in the different groups

From: Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal

n = 4

Sham

CM

CM + DMSO

CM + MPEP

Thickness of the PSD/nm

21.33 ± 0.8536

37.24 ± 1.1464*

39.25 ± 1.2172*

19.74 ± 0.9326#

Width of the synaptic cleft/nm

19.29 ± 1.5273

32.13 ± 1.2319*

30.87 ± 2.0146*

20.92 ± 1.5236#

Active zones/nm

315 ± 24.58

496 ± 18.40*

507 ± 28.54*

342 ± 20.27#

Synaptic interface curvature

1.03 ± 0.0021

1.36 ± 0.02537*

1.39 ± 0.0725*

1.12 ± 0.02527#

  1. n the number of rats. Date are presented as the mean ± SD. *p < 0.05 compared with the sham group; #p < 0.05 compared with the CM + DMSO group