Table 2 Characteristics of Study Population based on Headache Phenotype Diagnosis following Diary Review
Variable | Chronic Migraine-Like (n = 47) | Episodic Migraine-Like combined with TTH-Like (n = 9) | Chronic TTH-Like (n = 8) |
|---|---|---|---|
Age, mean (SD), y | 34.5 (12.0) | 34.3 (7.9) | 31.5 (8.0) |
Male/Female, % | 19/81 | 33/67 | 37/63 |
Body Mass Index, mean (SD), kg/m2 | 26.1 (5.6) | 24.6 (3.8) | 24.9 (4.0) |
Current Employment Status, No. of subjects (%) | |||
Full-time employed | 10 (21) | 2 (22) | 2 (25) |
Part-time employed | 25 (53) | 4 (44) | 5 (63) |
Unemployed | 11 (23) | 2 (22) | 1 (13) |
Retired | 1 (2) | 1 (11) | 0 (0) |
Education | |||
Years of education, mean (SD), y | 14.3 (2.6) | 16.3 (3.2) | 15.9 (3.3) |
Level of education, No. of subjects (%) | |||
Secondary school or high school | 10 (21) | 0 (0) | 1 (13) |
Skilled labor | 13 (28) | 4 (44) | 1 (13) |
Bachelor’s degree | 11 (23) | 3 (33) | 3 (38) |
Higher education | 13 (28) | 2 (22) | 3 (38) |
Injury Cause, No. of subjects, % | |||
Fall | 12 (26) | 3 (33) | 3 (38) |
Motor vehicle collision | 14 (30) | 2 (22) | 1 (13) |
Sports-related injury | 11 (23) | 1 (11) | 1 (13) |
Violence/assault | 1 (2) | 1 (11) | 1 (13) |
Other unintentional injury | 9 (19) | 2 (22) | 2 (25) |
Months with Headache attributed to Mild TBI, mean (SD), months | 55.0 (55.1) | 89.0 (73.4) | 70.0 (58.0) |
Family History of Migraine, No. of subjects (%) | 15 (32) | 4 (44) | 3 (38) |
Headache Frequency, mean (SD) | |||
Monthly headache days of any intensity | 26.6 (2.4) | 24.6 (3.8) | 26.6 (3.6) |
Monthly headache days of moderate to severe intensity | 19.9 (6.5) | 17.7 (7.0) | 20.3 (5.9) |
Migraine-Like Frequency, mean (SD) | |||
Monthly migraine-like days | 22.5 (6.8) | 3.6 (1.9) | – |
Monthly definite migraine-like days | 17.6 (8.4) | 3.0 (2.1) | – |
Monthly probable migraine-like days | 4.8 (6.1) | 0.6 (1.1) | – |
TTH-Like Frequency, mean (SD) | |||
Monthly TTH-like days | 4.1 (6.3) | 21.0 (4.6) | 26.6 (3.6) |
Acute Medication Use | |||
Current Acute Medication Use, No. of subjects (%) | 44 (94) | 7 (78) | 7 (88) |
Triptans | |||
Current or previous use, No. of subjects | 24 | 5 | 1 |
Lack of efficacy in those with history of acute medication use, No. of subjects (%) | 13 (54) | 3 (60) | 1 (100) |
Prevention Medication Use | |||
History of Preventive Medication Use, No. of subjects (%) | 36 (77) | 7 (78) | 6 (75) |
No drug failures, No. of subjects (%) | 4 (11) | 2 (29) | 1 (17) |
Failure of ≥2 drugs, No. of subjects (%) | 20 (56) | 5 (71) | 2 (33) |
Preventive Treatment Naïve, No. of subjects | 11 (23) | 2 (22) | 2 (25) |
Current Preventive Medication Use, No. of subjects (%) | 20 (43) | 5 (56) | 4 (50) |