Factors associated with the presence of headache in hospitalized COVID-19 patients and impact on prognosis: a retrospective cohort study

Table 2 Predictors of mortality: univariate and multivariate logistic regression analysis

	Type of analysis	OR	95% CI	p-value
mRS > 2	Univariate	11.371	6.376–20.278	< 0.001
mRS > 2	Multivariate	3.714	1.880–7.338	< 0.001
Age	Univariate	1.090	1.069–1.112	< 0.001
Age	Multivariate	1.058	1.055–1.031	< 0.001
Female sex	Univariate	0.682	0.454–1.024	0.065
Female sex	Multivariate	0.703	0.413–1.196	0.194
Hypertension	Univariate	3.534	2.272–5.495	< 0.001
Hypertension	Multivariate	1.379	0.802–2.370	0.245
Diabetes	Univariate	2.129	1.353–3.351	0.001
Diabetes	Multivariate	1281	0.739–2.221	0.377
Smoking	Univariate	1.589	1.004–2.514	0.048
Smoking	Multivariate	1.907	0.997–3.275	0.051
Cardiological disorders	Univariate	2.955	1.950–4.478	< 0.001
Cardiological disorders	Multivariate	1.263	0.760–2.100	0.368
Pulmonary disorders	Univariate	1.434	0.928–2.217	0.105
Pulmonary disorders	Multivariate	0.898	0.517–1.559	0.702
Cancer	Univariate	1.641	1.001–2.690	0.049
Cancer	Multivariate	1.254	0.694–2.266	0.453
Chronic neurological disorders	Univariate	3.961	2.516–6.234	< 0.001
Chronic neurological disorders	Multivariate	1.659	0.947–2.906	0.077
Immunosuppression	Univariate	1.295	0.405–4.138	0.663
Headache	Univariate	0.167	0.079–0.351	< 0.001
Headache	Multivariate	0.399	0.175–0.906	0.028
Time between onset of symptoms and ED visit	Univariate	0.908	0.870–0.947	< 0.001
Time between onset of symptoms and ED visit	Multivariate	0.962	0.925–1.000	0.050

OR Odds Ratio, CI Confidence-interval, mRS Modified Rankin scale, ED Emergency department

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