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Table 3 Proposed updated definition of resistant and refractory migraine

From: European headache federation consensus on the definition of resistant and refractory migraine

  1. aTrials with at least 3 drug classes is encouraged if allowed by contraindications
  2. bEstablished doses and duration as reported in Table 4
  3. cAbsolute, major and relative contraindications as reported in Table 5
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