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Table 5 Logistic regression modeling triptan insufficient response with backward selection results. P-values in bold indicate statistically significant factors (N = 1033)

From: A global real-world assessment of the impact on health-related quality of life and work productivity of migraine in patients with insufficient versus good response to triptan medication

 

Odds ratio estimates

 

Factor

Effect

Point estimate

95% Wald confidence intervals

p-value

Agea

 

0.999

0.988, 1.011

0.930

Sexa

Female vs Male

0.920

0.663, 1.277

0.612

Currently taking OTC medications for migrainesa

Yes vs No

1.465

1.000, 2.147

0.050

When do you usually take your prescribed acute medication?a

After pain has started and I have an idea of how severe it is vs At first sign of a migraine (before pain starts)

2.433

1.258, 4.703

0.008

 

When pain starts vs At first sign of a migraine (before pain starts)

1.726

1.252, 2.380

0.001

On average, per month over the last 3 months: No. of migraine-related headache daysb

 

0.926

0.856, 1.002

0.057

MSQ domain: Preventivea

 

0.980

0.968, 0.992

0.001

MSQ domain: Emotionala

 

0.981

0.970, 0.992

0.001

EQ-5D utility scoresa

 

0.106

0.032, 0.355

< 0.001

Total headache days (including migraine, tension, rebound, etc.) per month in last 3 monthsb

 

1.095

1.023, 1.174

0.010

How severe have the patient’s migraine attacks been over the last 3 months?b

 

1.025

1.003, 1.048

0.027

  1. aPatient reported. bPhysician reported
  2. The results in the table are from a backward logistic regression with a significance level of 0.1 for a variable to stay in the model. A total of 380 patients (380/1413; 26.8%) were excluded from the analyses due to missingness of variables
  3. EQ-5D = EuroQol 5-Dimensions questionnaire; MSQ = Migraine-Specific Quality of Life Questionnaire; OTC = over-the-counter