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Table 3 Age- and multivariable-adjusted hazard ratios for all-cause and disease-specific mortality according to migraine subtypes or non-migraine headache status (N = 27,844)

From: Migraine, headache, and mortality in women: a cohort study

Migraine or headache status:No history, (N = 18,691)Non-migraine headache, (N = 4025)Migraine with aura, (N = 1435)Migraine without aura, (N = 2175)Past history of migraine, (N = 1518)
HR -ref-HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)
All-cause death,N3614641198253306
Age-adjusteda1 (ref)1.04 (0.96–1.13)0.96 (0.83–1.11)0.86 (0.76–0.98)1.02 (0.91–1.15)
MV-adjustedb1 (ref)1.01 (0.93–1.10)0.99 (0.85–1.14)0.91 (0.80–1.03)1.00 (0.88–1.12)
Cardiovascular death,N28146221225
Age-adjusteda1 (ref)1.08 (0.79–1.47)1.55 (1.00–2.39)0.64 (0.36–1.14)1.08 (0.72–1.63)
MV-adjustedb1 (ref)0.99 (0.72–1.35)1.64 (1.06–2.54)0.68 (0.38–1.22)1.03 (0.68–1.55)
Cancer death,N861164488566
Age-adjusteda1 (ref)1.01 (0.86–1.20)0.86 (0.64–1.15)1.04 (0.83–1.30)0.94 (0.73–1.20)
MV-adjustedb1 (ref)1.02 (0.86–1.21)0.89 (0.67–1.19)1.09 (0.87–1.37)0.93 (0.72–1.19)
Female-specific cancercdeath,N24841122615
Age-adjusteda1 (ref)0.86 (0.61–1.19)0.72 (0.40–1.29)1.05 (0.70–1.58)0.74 (0.44–1.25)
MV-adjustedb1 (ref)0.87 (0.62–1.21)0.74 (0.41–1.32)1.08 (0.72–1.62)0.75 (0.45–1.27)
  1. Abbreviations: HR Hazard ratio, CI Confidence interval, ref, reference category; MV-adjusted, multivariable-adjusted
  2. aAdjusted for age at baseline
  3. bAdjusted for the following variables measured at baseline: age, BMI, total cholesterol, smoking, alcohol use, physical activity, diabetes, hypertension, family history of myocardial infarction, and family history of cancer
  4. cIncludes breast cancer, cervical cancer, endometrial cancer, ovarian cancer, and uterine cancer
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