| Study sub-groups | P value* | |||
---|---|---|---|---|---|
Patients with migraine with aura | Patients with migraine without aura | ||||
Vitamin D | Placebo | Vitamin D | Placebo | ||
Number of Headache Days per month | |||||
 Baseline | 10.58 (3.67) a,b | 7.75 (3.86) | 6.81 (2.43) a | 7.67 (3.29) b | 0.008 |
 After the trial | 6.00 (3.45) | 7.50 (3.32) | 4.63 (2.40) a | 7.17 (4.11) a | 0.029 |
 Changes | −4.58 (3.76) a,b | −0.25 (3.05) a | −2.09 (2.27) | − 0.10 (2.91) b | 0.000 |
P value# | 0.001 | 0.801 | < 0.001 | 0.868 |  |
Migraine Related Disability (MIDAS score) | |||||
 Baseline | 40.00 (26.38) | 37.90 (18.53) | 24.81 (10.80) | 36.53 (22.75) | 0.057 |
 After the trial | 23.08 (24.42) | 42.90 (25.15) a | 17.59 (10.94) a.b | 32.46 (16.44) b | 0.001 |
 Changes | −16.92 (15.39) a,b | 5.00 (20.18) a | −7.22 (9.25) | −1.46 (12.20) b | 0.001 |
P value# | 0.002 | 0.453 | < 0.001 | 0.547 |  |