Skip to main content

Table 4 Burden of illness in patients with episodic migraine and chronic migraine: patient self-completion form data

From: Real-world treatment patterns and patient-reported outcomes in episodic and chronic migraine in Japan: analysis of data from the Adelphi migraine disease specific programme

Patient-reported outcomes

Cohort

Total

(N = 634)

p-value

Episodic migraine

0–3 HDM

(n = 331)

Episodic migraine

4–7 HDM

(n = 183)

Episodic migraine

8–14 HDM

(n = 86)

Chronic migraine

≥15 HDM

(n = 34)

MIDAS total score, mean (SD)

4.8 (12.6)

11.0 (26.2)

15.7 (18.3)

21.3 (22.0)

8.9 (19.4)

< 0.001a

MIDAS disability category, n (%)

     

< 0.001b

 Little/no disability

191 (74.9)

86 (57.7)

29 (39.7)

6 (30.0)

312 (62.8)

 

 Mild disability

32 (12.5)

25 (16.8)

14 (19.2)

2 (10.0)

73 (14.7)

 

 Moderate disability

20 (7.8)

17 (11.4)

7 (9.6)

5 (25.0)

49 (9.9)

 

 Severe disability

12 (4.7)

21 (14.1)

23 (31.5)

7 (35.0)

63 (12.7)

 

Derived Japanese EQ-5D utility score, mean (SD)

0.89 (0.16)

0.86 (0.18)

0.82 (0.19)

0.72 (0.23)

0.86 (0.18)

< 0.001a

EQ-5D overall VAS score, mean (SD)

73.8 (17.9)

72.5 (16.9)

68.8 (18.4)

60.8 (22.6)

72.1 (18.2)

< 0.001a

WPAI score, mean (SD)

 % Work time missed

4.5 (16.1)

4.4 (13.3)

2.8 (9.7)

8.5 (18.6)

4.4 (14.6)

0.562a

 % Impairment at work

29.5 (25.5)

35.8 (27.6)

37.3 (29.4)

42.2 (25.1)

33.0 (26.9)

0.051a

 % Overall work impairment

30.5 (26.7)

37.0 (28.9)

38.1 (29.4)

44.7 (28.0)

34.2 (28.0)

0.058a

 % Activity impairment

32.4 (28.0)

40.1 (28.0)

46.1 (28.8)

55.0 (28.0)

37.7 (28.8)

< 0.001a

  1. Continuous variables are reported as mean (SD) for non-missing observations; percentages are calculated as proportion of non-missing data. MIDAS score 0–5 = little or no disability; MIDAS score 6–10 = mild disability; MIDAS score 11–20 = moderate disability; MIDAS score > 21 = severe disability; higher EQ-5D utility and VAS scores indicate higher general health status and quality of life, respectively
  2. EQ-5D, EuroQol-5 Dimensions; HDM, headache days per month; MIDAS, Migraine Disability Assessment; SD, standard deviation; VAS, visual analog scale; WPAI, Work Productivity and Activity Impairment
  3. aAnalysis of variance analyses
  4. bFisher’s exact test