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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Effects of two isometheptene enantiomers in isolated human blood vessels and rat middle meningeal artery – potential antimigraine efficacy

Fig. 3

Effect of i.v. bolus injections of isometheptene enantiomers or the racemate (3 mg/kg) on dural vasodilation induced by periarterial electrical stimulation (150–300 μA, upper panels), capsaicin (10 μg/kg, middle panels) or α-CGRP (1 μg/kg, lower panels) in anesthetized rats (n = 4 in each group); (S)-IMH, (S)-isometheptene; (R)-IMH, (R)-isometheptene; (RS)-IMH, isometheptene racemate

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