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Table 3 Association between response to OnabotA and SNP rs222749 in gene TRPV1

From: CALCA and TRPV1 genes polymorphisms are related to a good outcome in female chronic migraine patients treated with OnabotulinumtoxinA

     P value Odds ratio (95% CI)
POPULATION RESPONSE GENOTYPES MINOR ALLELE FREQUENCY (%) GENOTYPIC FREQUENCY ALLELE FREQUENCY ALLELE A RECESIVITY HYPOTHESIS ALLELE A DOMINANCE HYPOTHESIS Dominant model Codominant model Recessive model
GG GA AA
n = 156 Responders (n = 120) 111 8 1 4,2 0,040 0,021 0,013 0,102 2,47 (0,81-7,48) 2,40 (0,80-7,24) 10,82 (1,09-107,45)
Non-responders (n = 36) 30 3 3 12,5
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