From: Increased connectivity of pain matrix in chronic migraine: a resting-state functional MRI study
 | Episodic migraine (n = 44) | Chronic migraine (n = 18) | P |
---|---|---|---|
Age (range) | 40 ± 10.2 (22–57) | 41.4 ± 10.9 (19–55) | 0.622 |
Female sex | 36 (81.82%) | 11 (61.11%) | 0.084 |
Disease duration, y | 12.0 ± 9.0 | 12.9 ± 9.9 | 0.822 |
Headache days per month | 6.3 ± 3.6 | 23 ± 5.9 | < 0.001 |
Moderate/severe headache days per month | 4.3 ± 2.7 | 13.3 ± 7.9 | < 0.001 |
Migraine with aura | 4 (9.09%) | 4 (22.22%) | 0.214 |
Allodynia | 8 (18.18%) | 5 (27.78%) | 0.400 |
Anxiety | 15 (34.09%) | 9 (50%) | 0.243 |
Depression | 6 (13.64%) | 6 (33.33%) | 0.075 |