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Fig. 4 | The Journal of Headache and Pain

Fig. 4

From: Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries

Fig. 4

Human intracranial arteries were pre-contracted with 30 mM potassium buffer. The curves show dilatation in response to increasing concentrations of VIP 10− 11 to 10− 7 M in the presence of 66.7 nM of the monoclonal antibody against CGRP (fremanezumab) or an isotype control (KLH). The data show mean ± SEM, n = 2–4 for each concentration. K:potassium; TEV:Teva; VIP:vasoactive intestinal peptide

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The Journal of Headache and Pain

ISSN: 1129-2377

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