Fig. 2From: Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteriesHuman intracranial arteries were pre-contracted with 30 mM potassium buffer. The curves show dilatation in response to increasing concentrations of αCGRP 10− 11 to 10− 7 M in the presence of 66.7 nM of the monoclonal antibody against CGRP (fremanezumab) or an isotype control (KLH). The data show mean ± SEM, n = 2–4 for each concentration. CGRP:calcitonin gene-related peptide; K:potassium; TEV:TevaBack to article page