Parameters | Patients | Healthy volunteers | p-value |
---|---|---|---|
Age | 32.9 ± 14.5 | 31.45 ± 13.94 | p = 0.63 |
Gender | 17 F | 19 F | – |
N° of headache days per month | 24.88 ± 7.22 | – | – |
Medication Overuse Headache | 12 (70%) | – | – |
Type of medication overused |  | – | – |
Triptans: 4 (33%) | Â | Â | |
NSAIDs: 7 (58%) | Â | Â | |
Combination: 1 (8%) | Â | Â | |
N° of acute medication per month | 16.18 ± 12.31 | – | – |
Pain intensity (1–3 scale) | 1point 0 pts |  |  |
2 points 3 pts | – | – | |
3 points 15 pts | Â | Â | |
Habituation N1P1 at T0 | 0.23 ± 0.68 | 0.26 ± 0.63 | p = 0.53 |
Habituation P1N2 at baseline | 0.20 ± 0.55 | 0.08 ± 0.53 | p = 0.54 |
IDAP at baseline | 0.76 ± 0.95 | 0.03 ± 0.76 | p = 0.01* |