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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Neurophysiological correlates of clinical improvement after greater occipital nerve (GON) block in chronic migraine: relevance for chronic migraine pathophysiology

Fig. 3

Responders vs. No-responders difference in early neurophysiological responses after GON-B. One week after the GON-B responders had no change in N1P1 response. For P1N2 component of habituation both Responders and Non-responders had a trend towards the reduction of habituation degree (although not significant, p = 0.11). No significant difference was found after multiple comparison tests. On the other hand, CM patients had an early reduction in IDAP slope, corresponding to an increase in serotonin firing, after GON-B (p = 0.008), with a significant difference at multiple comparison tests in Responders vs. Non-responders (p = 0.004). Responders are in dotted, No-responders in continuous line

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