| Odds ratio | 95% CI | p-value |
---|---|---|---|
Study 1 (EVOLVE-1) | |||
 Week 1 | 2.71 | 2.00, 3.66 | <0.001 |
 Week 2 | 3.08 | 2.27, 4.17 | <0.001 |
 Week 3 | 2.11 | 1.55, 2.86 | <0.001 |
 Week 4 | 1.56 | 1.15, 2.11 | 0.004 |
Study 2 (EVOLVE-2) | |||
 Week 1 | 2.88 | 2.16, 3.86 | <0.001 |
 Week 2 | 2.76 | 2.07, 3.68 | <0.001 |
 Week 3 | 2.41 | 1.80, 3.22 | <0.001 |
 Week 4 | 2.67 | 1.99, 3.58 | <0.001 |