Table 2 Incidence and hazard ratios of mortality and associated risk factors
From: Survival outcome and mortality rate in patients with migraine: a population-based cohort study
HR (95% CI) | ||||||
|---|---|---|---|---|---|---|
Event no | Person-years | Rate | Crude | Adjusteda | Adjusteda | |
Migraine | ||||||
None | 5567 | 582,126 | 9.74 | 1.00 | 1.00 | |
Total | 1167 | 146,776 | 7.95 | 0.82(0.77, 0.87)*** | 0.81(0.76, 0.87)*** | |
Status migrainosus | 401 | 44,471 | 9.02 | 0.92(0.83, 1.02) | 0.89(0.80, 0.98)* | 1.00 |
Non-status migraine | 766 | 102,304 | 7.49 | 0.77(0.72, 0.83)*** | 0.78(0.72, 0.84)*** | 0.89(0.79, 0.99)* |
Age, year | ||||||
20–49 | 1753 | 475,258 | 3.69 | 1.00 | 1.00 | 1.00 |
50–64 | 1667 | 171,118 | 9.74 | 2.65(2.48, 2.84)*** | 2.57(2.40, 2.75)*** | 3.05(2.58, 3.61)*** |
65+ | 3414 | 82,525 | 41.4 | 11.4(10.8, 12.1)*** | 10.5(9.84, 11.1)*** | 12.4(10.6, 14.4)*** |
Sex | ||||||
Female | 3693 | 538,264 | 6.86 | 1.00 | 1.00 | 1.00 |
Male | 3141 | 190,637 | 16.5 | 2.41(2.29, 2.52)*** | 1.78(1.70, 1.87)*** | 1.96(1.74, 2.21)*** |
Comorbidity | ||||||
Depression | ||||||
No | 5771 | 643,710 | 8.97 | 1.00 | 1.00 | 1.00 |
Yes | 1063 | 85,192 | 12.5 | 1.41(1.32, 1.50)*** | 1.33(1.24, 1.43)*** | 1.27(1.07, 1.52)** |
Mental disorders | ||||||
No | 2279 | 320,327 | 7.11 | 1.00 | 1.00 | 1.00 |
Yes | 4555 | 408,575 | 11.2 | 1.56(1.49, 1.64)*** | 1.19(1.12, 1.27)*** | 1.19(1.02, 1.39)* |
Insomnia | ||||||
No | 1985 | 263,064 | 7.55 | 1.00 | 1.00 | 1.00 |
Yes | 4849 | 465,838 | 10.4 | 1.41(1.34, 1.48)*** | 0.95(0.89, 1.00) | 1.05(0.92, 1.21) |
Alcohol-related illness | ||||||
No | 6367 | 708,326 | 8.99 | 1.00 | 1.00 | 1.00 |
Yes | 467 | 20,575 | 22.7 | 2.61(2.37, 2.86)*** | 2.18(1.98, 2.40)*** | 1.95(1.53, 2.49)*** |
Anxiety | ||||||
No | 3970 | 463,834 | 8.56 | 1.00 | 1.00 | 1.00 |
Yes | 2864 | 265,067 | 10.8 | 1.27(1.21, 1.33)*** | 0.81(0.76, 0.87)*** | 0.79(0.67, 0.92)** |