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Table 9 Studies of SPG block for musculoskeletal pain

From: Sphenopalatine ganglion: block, radiofrequency ablation and neurostimulation - a systematic review

Musculoskeletal pain

Author

Year

Medical problems

Approach

Imaging

Medication

Number of cases

Study design

Outcome

Amster et al. [28]

1948

Lumbosacral and sacroiliac pain

Cotton tipped applicator, transnasal approach

None

Nupercaine, pontocaine, monocaine

61

Case series

Relief of pain and spasm in 90% of cases

Ruskin et al. [29]

1946

Lumbo-sacral spasm

Unknown

None

Cocaine, novocaine or nupercaine

36

Case series

Pain partially or completely relieved with SPGB and intramuscular injections of ironyl and calcium ascorbate

Berger et al. [32]

1986

Low back pain

Cotton tip applicator and transnasal needle

None

Cocaine or lidocaine

7 cases with cocaine, 7 cases with lidocaine, 7 controls

Case-control

No statistical significance between cases and controls

Scudds et al. [3]

1995

Chronic muscle pain syndrome

Cotton tipped applicator, transnasal approach

None

4% lidocaine

42 with fibromyalgia, 19 with myofascial pain syndrome

Double-blind randomized controlled

No statistical significance between 4% lidocaine and placebo

Janzen et al. [30]

1997

Myofascial pain syndrome and fibromyalgia

Nasal spray

None

4% lidocaine

42 with fibromyalgia, 19 with myofascial pain syndrome

Double-blind, placebo-controlled

No statistical significance between 4% lidocaine and placebo

Ferrante et al. [31]

1998

Myofascial pain syndrome of the head, neck and shoulders

NA

None

4% lidocaine

13 cases, 7 controls

Double-blind, placebo-controlled, crossover design

No statistical significance