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Table 1 Distribution of KATP channels

From: The KATP channel in migraine pathophysiology: a novel therapeutic target for migraine

Subtypes of KATPchannels

Tissue expression

Migraine related structures

Kir6.2/SUR1

Pancreas and brain

DRG, TG and TNC from rats (20–24, 26).

Kir6.2/SUR2A

Cardiac and skeletal muscle

 

Kir6.2/SUR2B

Smooth muscle

DRG, TG, TNC, BA and MCA from rats(20–24, 26).

Kir6.1/SUR2B

Smooth muscle

MMA from rats, pigs and human; MCA from rats and pigs; BA, DRG, TG and TNC from rats (20–24, 26).

  1. DRG Dorsal root ganglia, TG trigeminal ganglion, TNC trigeminal nucleus caudatus, BA basilar artery, MMA middle meningeal artery, MCA middle cerebral artery