From: The comorbidity burden of patients with cluster headache: a population-based study
Definite n = 75 | Control n = 152 | Unconfirmed n = 22 | ||
---|---|---|---|---|
Mean age in years (range) | 43.4 (20–74) | 44 (20–74) | ||
Proportion of males | 80% | 80% | 45% | |
Comorbidity | % | % | % | p value definite v controls Pearson chi-square |
Attention deficit disorder | 4 | 2 | 0 | 0.4 |
Anxiety | 7 | 8 | 18 | 0.7 |
Arthritis/Rheumatologic condition | 15 | 11 | 14 | 0.4 |
Asthma | 7 | 7 | 0 | 1 |
Back pain/Spine condition | 17 | 14 | 14 | 0.56 |
Celiac disease | 1 | 0 | 0 | 0.32 |
Cerebrovascular disease | 1 | 1 | 0 | 1 |
Cigar smoking | 4 | 1 | 0 | 0.17 |
Cigarette smoking | 64 | 32 | 31 | 0.00077*** |
Congenital disease | 0 | 3 | 0 | 0.08 |
COPD | 1 | 1 | 0 | 1 |
Cardiovascular disease | 15 | 16 | 36 | 0.85 |
Dental/TMJ | 4 | 0 | 5 | 0.04* |
Depression | 17 | 7 | 23 | 0.03* |
Deviated septum | 7 | 1 | 5 | 0.03* |
Diabetes | 0 | 9 | 5 | 0.002** |
Divorce | 13 | 7 | 14 | 0.16 |
Endocrine | 8 | 3 | 9 | 0.12 |
Alcohol abuse | 17 | 8 | 5 | 0.054 |
Alcohol moderate | 1 | 3 | 0 | 0.31 |
Fibromyalgia | 5 | 1 | 0 | 0.1 |
GERD | 8 | 10 | 9 | 0.62 |
GI procedures | 7 | 8 | 0 | 0.79 |
Glaucoma/Ocular | 3 | 3 | 5 | 1 |
Head trauma | 5 | 1 | 9 | 0.1 |
Hematologic | 3 | 7 | 14 | 0.19 |
Hyperlipidemia | 25 | 25 | 32 | 1 |
Hypertension | 15 | 22 | 18 | 0.2 |
Irritable bowel syndrome | 4 | 1 | 14 | 0.17 |
Infectious | 5 | 4 | 9 | 0.73 |
Malignancy | 9 | 16 | 14 | 0.13 |
Marijuana | 8 | 4 | 9 | 0.23 |
Musculoskeletal/Ortho | 7 | 16 | 5 | 0.046* |
Nephrolithiasis | 7 | 2 | 0 | 0.08 |
Ob/Gyn | 4 | 5 | 0 | 0.73 |
Obesity | 3 | 7 | 9 | 0.19 |
Other GI | 9 | 24 | 5 | 0.004** |
Other Headache | 5 | 3 | 5 | 0.47 |
Other Neurologic | 4 | 7 | 9 | 0.35 |
Other Pain, e.g. fibromyalgia | 3 | 5 | 0 | 0.47 |
Other Psychiatric disorder | 7 | 5 | 14 | 0.55 |
Other sleep | 3 | 5 | 5 | 0.47 |
Other Substance abuse | 3 | 4 | 9 | 0.7 |
Peptic ulcer disease | 4 | 1 | 9 | 0.17 |
Renal | 1 | 3 | 0 | 0.31 |
Restless legs | 0 | 0 | 0 | 1 |
Seizure disorder | 5 | 5 | 5 | 1 |
Sinus problems | 5 | 8 | 9 | 0.39 |
Skin conditions | 4 | 19 | 5 | 0.0008*** |
Sleep apnea | 9 | 5 | 5 | 0.27 |
Suicide attempt | 0 | 1 | 0 | 0.32 |
Tendinitis | 7 | 3 | 5 | 0.19 |
Trigeminal neuralgia | 0 | 0 | 0 | 1 |
Urologic | 5 | 10 | 5 | 0.18 |
Vascular malformation | 1 | 0 | 0 | 0.32 |
Violent trauma | 0 | 2 | 0 | 0.16 |