Table 3 Side effects/Adverse events occurring in any group and ranked by overall incidence
Side effects/Adverse events | Topiramate N = 344 | Placebo N = 139 |
|---|---|---|
Paresthesia | 71(20.64)a | 4(2.88) |
Upper respiratory tract infection | 54(15.7) | 16(9.35) |
Fatigue | 48(13.95) | 11(7.91) |
Weight decrease | 39(11.34) | 5(3.59) |
Abdominal pain | 22(6.40) | 12(8.63) |
Anorexia | 26(7.56) | 7(5.03) |
Dry mouth | 26(7.56) | 4(2.88) |
Pharyngitis | 16(4.65) | 13(9.35) |
Memory impairment | 24(6.98) | 3(2.16) |
Injury | 16(4.65) | 11(7.91) |
Cognitive disorder | 23(6.69) | 4(2.88) |
Aphasia | 23(6.69) | 3(2.16) |
Sinusitis | 14(4.07) | 7(5.03) |
Nausea | 11(3.20) | 5(3.59) |
Altered mood | 14(4.07) | 2(1.44) |
Dizziness | 14(4.07) | 1(0.72) |
Somnolence | 11(3.20) | 3(2.16) |
Gastroenteritis | 10(2.91) | 3(2.16) |
Fever | 10(2.91) | 2(1.44) |
Influenza-like symptoms | 8(2.33) | 2(1.44) |
Sedation | 4(1.16) | 2(1.44) |
Rhintis | 5(1.45) | 1(0.72) |
Insomnia | 4(1.16) | 1(0.72) |
Viral infection | 4(1.16) | 1(0.72) |
Back pain | 2(0.58) | 3(2.16) |
Conjunctivitis | 4(1.16) | 1(0.72) |
Lack of concentration in school# | 4(1.16) | 0(0) |
Coughing# | 4(1.16) | 0(0) |
Taste perversion# | 4(1.16) | 0(0) |
Abnorma vision | 3(0.87) | 1(0.72) |
Eye pain | 2(0.58) | 2(1.44) |
Vomiting | 2(0.58) | 1(0.72) |
Nervousness# | 3(0.87) | 0(0) |
Asthma# | 2(0.58) | 0(0) |
Pneumonia# | 2(0.58) | 0(0) |
Allergy# | 2(0.58) | 0(0) |
Respiratory:bronchospasm | 1(0.29) | 1(0.72) |
Suicide attempt# | 1(0.29) | 0(0) |
Intussusception# | 1(0.29) | 0(0) |
Traumatic liver injury# | 1(0.29) | 0(0) |