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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: The NO-cGMP-PKG signal transduction pathway is involved in the analgesic effect of early hyperbaric oxygen treatment of neuropathic pain

Fig. 1

MWT and TWL in all rats bothpreoperatively and postoperatively. HBO treatment was performed once daily for five consecutive days beginning from the first day after CCI, as indicated by arrows. NS, DMSO, L-NAME, ODQ and KT5823 were intrathecally delivered once daily half an hour after HBO treatment. a Changes on mechanical allodynia. b Changes on thermal hyperalgesia. Comparison of TWL and MWT in rats: *P < 0.05 vs. CCI; # P < 0.05 vs. HBO. N = 6 rats for each group. HBO treatment at early stages alleviates neuropathic pain; L-NAME, ODQ and KT5823 can reverse HBO effect

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The Journal of Headache and Pain

ISSN: 1129-2377

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