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Table 4 Summary of glutamate immunostaining in TNC for different treatment groups

From: Topical dura mater application of CFA induces enhanced expression of c-fos and glutamate in rat trigeminal nucleus caudalis: attenuated by KYNA derivate (SZR72)

Group

Neuronal staining

Fiber staining

Glial cell staining

Fresh

-\+

++

-\+

CFA 7d

+++

++

-\+

Saline 7d

+

++

-\+

CFA+ SZR72 one dose

-\+

++

-\+

CFA+ SZR72 repeated

-\+

++

-\+

CFA+ saline one dose

+++

++

-\+

CFA + saline repeated

+++

++

-\+