Altered functional connectivity architecture of the brain in medication overuse headache using resting state fMRI

Table 2 The brain regions with altered functional connectivity density over the whole brain among MOH, EM and NC

	Anatomic region	MNI-space			Cluster size	Peak T value
	Anatomic region	X	Y	Z	Cluster size	Peak T value
MOH < NC
	ParaHippocampal_R	21	−18	−18	12	3.88
MOH > NC
	Parietal_Inf_L	−54	−39	48	20	3.98
	SupraMarginal_R	51	−33	48	10	3.52
EM < NC
	Cingulum_Ant_L	0	27	21	32	5.2
	Frontal_Inf_Orb_R	15	15	−24	25	3.95
EM > NC
	Thalamus_L	−9	−27	12	112	4.91
	Caudate_R	15	9	21	73	4.79
	Thalamus_R	12	−27	9	91	4.47
	Frontal_Inf_Orb_L	−36	39	−3	62	4.34
MOH < EM
	Caudate_R	15	6	24	34	6.82
	Insula_L	−30	24	15	19	6.68

MNI Montreal Neurological Institute, X, Y, Z coordinates of the primary maximum of the cluster, MOH < NC decreased FCD in MOH compared with NC, MOH > NC increased FCD in MOH compared with NC, EM < NC decreased FCD in EM compared with NC, EM > NC increased FCD in EM compared with NC, MOH < EM decreased FCD in MOH compared with EM

ISSN: 1129-2377