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Fig 5 | The Journal of Headache and Pain

Fig 5

From: Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system

Fig 5

CGRP (pg/mg of protein) measured using an enzyme-linked immunosorbant assay to assess changes in the trigeminal nucleus caudalis at 1 day and 1 week endpoints. The effects of single and repetitive closed head injury (CHI and RCHI) on CGRP levels in the trigeminal nucleus caudalis (n = 6 at day 1 and n = 5 at week 1) and RCHI groups (n = 6/endpoint), **p < 0.01 and ***p < 0.001 compared to incision control (n = 6/endpoint), and ##p < 0.01 and ###p < 0.001 compared to CHI. RCHI was induced on 3 consecutive days

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