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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system

Fig. 1

Experimental design showing mild closed head injury groups (CHI) receiving either single (CHI) or repetitive CHI two or three consecutive days (CHI2, CHI3) or with one day of recovery between injuries. All groups underwent baseline behavior testing and post-operative testing for trigeminal allodynia at day 3 and week 1. Tissues were collected at either day 1 or week 1 endpoints for ELISA, western blot, or immunohistochemical analysis

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