Table 4 Meta-analysis of the association between BDNF rs6265 and rs2049046 polymorphism and migraine
rs number | Studies | W Vs M (allele model) | WW + WM Vs MM (dominant model) | WW Vs WM + MM (recessive model) | WW Vs MM (additive model) | WW Vs WM (additive model) | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | ||
rs6265(G/A) | 5 | 0.86 (0.76, 0.99) | 0.03 | 0.85 (0.56, 1.28) | 0.42 | 0.84 (0.72, 0.98) | 0.03 | 0.81 (0.53, 1.22) | 0.31 | 0.85 (0.72, 1.00) | 0.04 |
rs2049046(A/T) | 4 | 0.88 (0.79, 0.98) | 0.02 | 0.89 (0.75, 1.06) | 0.18 | 0.80 (0.67, 0.96) | 0.02 | 0.78 (0.62, 0.97) | 0.02 | 0.81 (0.67, 0.99) | 0.03 |