Fig. 2

Consistent depression of wheel running following repeated injections of 10% AITC onto the dura. a Administration of 10% AITC depressed wheel running for approximately 3 h on all three trials. The magnitude of depressed wheel running was greatest following the third AITC injection, especially during the second hour, although this difference did not reach statistical significance when total wheel revolutions during the 3 h following AITC administration were analyzed (see Fig b). n = 6–7/condition