Table 2 Association analysis results of SNPs with suggestive genome-wide significance
From: A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants
Index SNP | Position | Other SNPs in clump | Gene | A 1 | A 2 | A1-F case/controls | A1-F 1000G_all (1000G_EUR)a | P-value | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
rs1006417 | 14:41803291 | rs1782180, rs1779522, rs1778408, rs11157219, rs715334, rs12433558 |  | G | A | 0.11/0.26 | 0.19 (0.19) | 1.40 × 10−6 | 0.34 (0.21–0.55) |
rs12668955 | 7:31116168 |  | ADCYAP1R1 | G | A | 0.34/0.52 | 0.55 (0.50) | 9.10 × 10−6 | 0.48 (0.34–0.66) |
rs1495452 | 3:65834076 |  | MAGI1 | A | G | 0.55/0.38 | 0.39 (0.45) | 1.43 × 10−5 | 2.03 (1.48–2.79) |
rs2182605 | 1:117463537 |  | PTGFRN | G | A | 0.32/0.50 | 0.51 (0.48) | 1.80 × 10−5 | 0.49 (0.35–0.68) |
rs16895584 | 8:122518935 |  |  | A | G | 0.24/0.04 | 0.070 (0.054) | 1.85 × 10−5 | 3.50 (2.03–6.02) |
rs6469999 | 8:122415207 | rs13255877, rs7833779 |  | A | G | 0.31/0.17 | 0.46 (0.16) | 2.16 × 10−5 | 2.23 (1.56–3.19) |
rs1509957 | 10:64610718 | rs224308, rs10822065 |  | G | A | 0.60/0.43 | 0.43 (0.49) | 2.66 × 10−5 | 1.99 (1.44–2.74) |