Fig. 2

a Representation of the two significant Independent Components (IC) functional connectivity networks differing in migraine patients scanned between attacks (MO) compared with healthy volunteers (HV) separated by independent component analysis (ICA). All images have been coregistered into the space of the MNI template. Brain areas are respectively coloured in hot metal scale (IC15) or in azure-blue (IC20). The numbers beneath each image refer to the z coordinate in Talairach space. b The bar graph reflects FDR corrected correlation between the 2 ICs, p < 0.05, in HV and MO. c Time course of spontaneous blood oxygen level dependent (BOLD) activity recorded during resting state and extracted from each of the two significant ICs