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Table 4 Red flag signs pertinent with side-locked headaches

From: Side-locked headaches: an algorithm-based approach

Mnemonic (SNOOP4) [17]

Clinical descriptions

Secondary headaches

Systemic

Fever

Temporal Arteritis (TA), malignancy, infective pathology (sinus, eye, teeth, etc.)

Weight loss

TA, malignancy,

Cough and other chest symptoms

Carcinoma lung

Nasal symptoms

Sinus related headaches

Neurological

Opthalmoplegia (diplopia, ocular palsies)

Painful opthalmoplegia syndrome

Visual disturbances

Ocular (glaucoma, post sclertitis, other inflammatory pathologies), Optic Nerve (optic neuritis, TA), orbital causes.

cognitive, motor, sensory or cerebellar abnormality

Intracranial pathologies

Onset sudden

Peak within minutes

Cervical artery dissection

Onset after 50 years

New headache in elderly

TA, Malignancy, Glaucoma (after 40 years, acute or intermittent), cervicogenic headache

Pattern of headaches

Persistent & progressive

A large number of secondary headaches have persistent & progressive course

Pain other than head (i.e. headache with pain in eye, face, and neck)

Look for the pathologies at the site of maximum pain

Precipitated by provocative maneuvers

Referred to Fig. 4

papilledema

Intracranial pathologies