Fig. 8

BNP reduced the excitability of small DRG neurons. a: The representative action potentials triggered by depolarizing current stimulation (1 s duration; 200 pA) in the absence (before treatment) and presence (after treatment) of treatments including extracellular solution condition (ECS), 10 min BNP, and 3 h pretreatment of BNP without or with IBTX, respectively. b: The ratio of action potential halfwidth in small DRG neurons in the presence (after treatment) vs. absence (before treatment) of treatments. The action potential halfwidth was measured from the first action potential triggered by current injection. ***p < 0.001, treatment versus control. Error bars indicated S.E.M