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Fig. 4 | The Journal of Headache and Pain

Fig. 4

From: Brain natriuretic peptide suppresses pain induced by BmK I, a sodium channel-specific modulator, in rats

Fig. 4

Representative microphotographs showed the location and expression of BNP in CGRP-positive and IB4-positive small DRG neurons. Immunofluorescene staining for BNP (a, d) and CGRP (b, e) were co-localized (c, f) in control (a-c) at 2 days after i.pl. BmK I injection (d-f). Immunofluorescene staining for BNP (g, j) and IB4 (h, k) were co-localized (i, l) in control (g-i) at 2 days after i.pl. BmK I injection (j-i). m, ratio of CGRP-positive and IB4-positive small DRG neurons co-localized with BNP between control group and the group of 2 days after i.pl. BmK I injection. Scale bar, 50 μm

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