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Table 1 Demographic information of the subjects (mean ± SD)

From: Altered functional connectivity of the marginal division in migraine: a resting-state fMRI study

 

EM

CM

MOH + CM

NC

p value

N (F/M)

18 (14/4)

16 (12/4)

44 (35/9)

32 (24/8)

0.97

Age (years)

33.4 ± 11.0**

42.4 ± 8.7

42.3 ± 9.6

41.3 ± 10.8

0.01

Body mass index

21.3 ± 0.7

24.4 ± 0.7*

23.1 ± 0.4

22.5 ± 0.5

0.01

Education

4.4 ± 1.1

3.4 ± 1.3**

3.1 ± 1.2**

4.7 ± 1.0

0.00

Migraine duration (years)

12.4 ± 8.1

11.3 ± 9.3

17.8 ± 9.1*

-

0.02

Headache frequency (days/month)

3.5 ± 2.7

25.1 ± 5.9**

26.5 ± 5.0**

-

0.00

Pain intensity (VAS)

8.3 ± 1.5

7.9 ± 1.5

8.0 ± 1.4

-

0.46

Duration of headache chronicity/medication overuse (years)

-

3.0 ± 3.3

4.7 ± 4.8

-

0.20

Medication intake

4.9 ± 3.7

4.3 ± 3.8

119.7 ± 111.6**

-

0.00

HAMA

15.7 ± 9.9**

21.6 ± 10.9**

18.5 ± 8.7**

2.4 ± 1.5

0.00

HAMD

10.9 ± 7.3**

16.3 ± 10.5**

19.9 ± 11.9**

1.1 ± 0.9

0.00

MMSE (adjusted by education)

28.5 ± 0.7

26.9 ± 0.7

27.1 ± 0.5

28.3 ± 0.6

0.22

MoCA (adjusted by education)

26.1 ± 0.8

23.5 ± 0.9**

24.8 ± 0.6 *

26.9 ± 0.7

0.02

  1. * VAS visual anologue score, HAMA Hamilton anxiety scale, HAMD Hamilton depression scale, MMSE mini-mental state examination, MoCA the Montreal cognitive assessment, EM episodic migraine, CM chronic migraine, MOH + CM medication overuse headache plus with chronic migraine *:compared to NCs P < 0.05;**:compared to NCs P < 0.01