From: Altered functional connectivity of the marginal division in migraine: a resting-state fMRI study
EM | CM | MOH + CM | NC | p value | |
---|---|---|---|---|---|
N (F/M) | 18 (14/4) | 16 (12/4) | 44 (35/9) | 32 (24/8) | 0.97 |
Age (years) | 33.4 ± 11.0** | 42.4 ± 8.7 | 42.3 ± 9.6 | 41.3 ± 10.8 | 0.01 |
Body mass index | 21.3 ± 0.7 | 24.4 ± 0.7* | 23.1 ± 0.4 | 22.5 ± 0.5 | 0.01 |
Education | 4.4 ± 1.1 | 3.4 ± 1.3** | 3.1 ± 1.2** | 4.7 ± 1.0 | 0.00 |
Migraine duration (years) | 12.4 ± 8.1 | 11.3 ± 9.3 | 17.8 ± 9.1* | - | 0.02 |
Headache frequency (days/month) | 3.5 ± 2.7 | 25.1 ± 5.9** | 26.5 ± 5.0** | - | 0.00 |
Pain intensity (VAS) | 8.3 ± 1.5 | 7.9 ± 1.5 | 8.0 ± 1.4 | - | 0.46 |
Duration of headache chronicity/medication overuse (years) | - | 3.0 ± 3.3 | 4.7 ± 4.8 | - | 0.20 |
Medication intake | 4.9 ± 3.7 | 4.3 ± 3.8 | 119.7 ± 111.6** | - | 0.00 |
HAMA | 15.7 ± 9.9** | 21.6 ± 10.9** | 18.5 ± 8.7** | 2.4 ± 1.5 | 0.00 |
HAMD | 10.9 ± 7.3** | 16.3 ± 10.5** | 19.9 ± 11.9** | 1.1 ± 0.9 | 0.00 |
MMSE (adjusted by education) | 28.5 ± 0.7 | 26.9 ± 0.7 | 27.1 ± 0.5 | 28.3 ± 0.6 | 0.22 |
MoCA (adjusted by education) | 26.1 ± 0.8 | 23.5 ± 0.9** | 24.8 ± 0.6 * | 26.9 ± 0.7 | 0.02 |